No, it’s not possible to establish a peering connection to a VPC in a different region. It’s only possible to establish a peering connection to a VPC in the same region.
No, you cannot establish a peering connection between VPCs in different regions in AWS. VPC peering connections are only possible within the same region. If you need connectivity between VPCs in different regions, you would typically use VPN connections or AWS Direct Connect to establish communication between them.